Biotin Anti-Mouse/Human CD11b Antibody[M1/70]
Product Specifications
Background
CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
Abbreviation
CD11b
Gene ID
16409;3684
UniProt
P05555; P11215
Host
Rat
Reactivity
Human; Mouse
Target
CD11 antigen-like family member B; CD11b; CR-3 alpha chain; Integrin alpha-M; Itgam; Leukocyte adhesion receptor MO1
Clonality
Monoclonal
Clone
M1/70
Conjugation
Biotin
Applications
FCM
Field of Research
Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology; Innate Immunity; Neuroscience; Neuroscience Cell Markers
Concentration
0.5 mg/mL
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Do not freeze.
Citation 01
https://pubs.acs.org/doi/abs/10.1021/acs.jafc.4c01758
Recommended Usage
6
Isotype
Rat IgG2b, κ
Available Sizes
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