Biotin Anti-Mouse/Human CD11b Antibody[M1/70]

Product Specifications

Background

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Abbreviation

CD11b

Gene ID

16409;3684

UniProt

P05555; P11215

Host

Rat

Reactivity

Human; Mouse

Target

CD11 antigen-like family member B; CD11b; CR-3 alpha chain; Integrin alpha-M; Itgam; Leukocyte adhesion receptor MO1

Clonality

Monoclonal

Clone

M1/70

Conjugation

Biotin

Applications

FCM

Field of Research

Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology; Innate Immunity; Neuroscience; Neuroscience Cell Markers

Concentration

0.5 mg/mL

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Do not freeze.

Citation 01

https://pubs.acs.org/doi/abs/10.1021/acs.jafc.4c01758

Recommended Usage

Isotype

Rat IgG2b, κ

Available Sizes

Documents

Product Datasheet

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