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Purified Anti-Mouse/Human CD11b Antibody[M1/70]

Product Specifications

Background

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Abbreviation

CD11b

Gene ID

3684

UniProt

P05555; P11215

Host

Rat

Reactivity

Human; Mouse

Target

CD11 antigen-like family member B; CD11b; CR-3 alpha chain; Integrin alpha-M; Itgam; Leukocyte adhesion receptor MO1

Clonality

Monoclonal

Clone

M1/70

Conjugation

Unconjugated

Applications

FCM

Field of Research

Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology; Innate Immunity; Neuroscience; Neuroscience Cell Markers

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Citation 01

https://pubs.acs.org/doi/abs/10.1021/acsnano.4c18954

Citation 02

https://www.sciencedirect.com/science/article/pii/S1742706125000467

Citation 03

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484005/

Citation 04

https://www.sciencedirect.com/science/article/pii/S1567576923008287

Citation 05

https://www.sciencedirect.com/science/article/pii/S1567576920338145

Citation 06

https://www.tandfonline.com/doi/abs/10.2147/JIR.S482509

Citation 07

https://pmc.ncbi.nlm.nih.gov/articles/PMC11540834/

Citation 08

https://link.springer.com/article/10.1134/S0022093024040069

Recommended Usage

6

Isotype

Rat IgG2b, κ

Available Sizes

Frequently Asked Questions

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