AF/LE Purified Anti-Mouse/Human CD11b Antibody[M1/70]
Product Specifications
Background
CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
Abbreviation
CD11b
Gene ID
3684
UniProt
P05555; P11215
Host
Rat
Reactivity
Human; Mouse
Target
CD11 antigen-like family member B; CD11b; CR-3 alpha chain; Integrin alpha-M; Itgam; Leukocyte adhesion receptor MO1
Clonality
Monoclonal
Clone
M1/70
Conjugation
None (AF/LE)
Applications
FCM
Field of Research
Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology; Innate Immunity; Neuroscience; Neuroscience Cell Markers
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Citation 01
https://www.sciencedirect.com/science/article/pii/S1567576924001218
Citation 02
https://www.sciencedirect.com/science/article/pii/S0361923024000273
Citation 03
https://www.tandfonline.com/doi/abs/10.1080/08820139.2024.2321353
Recommended Usage
6
Isotype
Rat IgG2b, κ
Available Sizes
Documents
Frequently Asked Questions
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