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Elab Fluor® 647 Anti-Human CD32 Antibody[IV-3]

Product Specifications

Background

CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform) .

Abbreviation

CD32

Gene ID

2212

UniProt

P31994

Host

Mouse

Reactivity

Human

Target

IGFR2; CD32; CDw32; FCG2; FCGR2B; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; IgG Fc receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-b

Clonality

Monoclonal

Clone

IV-3

Conjugation

Elab Fluor®647

Applications

FCM

Field of Research

Immunology; Innate Immunity

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG2b, κ

Available Sizes

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