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APC Anti-Human CD58 Antibody[TS2/9.1]

Product Specifications

Background

CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI) -anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface.

Abbreviation

CD58

Gene ID

965

UniProt

P19256

Host

Mouse

Reactivity

Human

Target

Ag3; CD58; LFA3; Lymphocyte function-associated antigen 3; Surface glycoprotein LFA-3

Clonality

Monoclonal

Clone

TS2/9.1

Conjugation

APC

Applications

FCM

Field of Research

Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Product Datasheet

https://789.bio/ea/t8wnpc

Product MSDS

https://789.bio/eb/Cqn1eP

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG1, κ

Available Sizes

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