Purified Anti-Human CD58 Antibody[TS2/9.1]
Product Specifications
Background
CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI) -anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface.
Abbreviation
CD58
Gene ID
965
UniProt
P19256
Host
Mouse
Reactivity
Human
Target
Ag3; CD58; LFA3; Lymphocyte function-associated antigen 3; Surface glycoprotein LFA-3
Clonality
Monoclonal
Clone
TS2/9.1
Conjugation
Unconjugated
Applications
FCM
Field of Research
Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/4gcosc
Product MSDS
https://789.bio/eb/GC884G
Recommended Usage
6
Isotype
Mouse IgG1, κ
Available Sizes
Curated Selection
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