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Biotin Anti-Human CD35 Antibody[E11]

Product Specifications

Background

CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.

Abbreviation

CD35

Gene ID

1378

UniProt

P17927

Host

Mouse

Reactivity

Human

Target

C3BR; C3b/C4b receptor; CD35; CR1; Complement receptor type 1

Clonality

Monoclonal

Clone

E11

Conjugation

Biotin

Applications

FCM

Field of Research

Cell Biology; Complement; Immunology; Neuroinflammation; Neuroscience

Concentration

0.5 mg/mL

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Do not freeze.

Product Datasheet

https://789.bio/ea/jpmj54

Product MSDS

https://789.bio/eb/DmD48S

Recommended Usage

6

Isotype

Mouse IgG1, κ

Available Sizes

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