Biotin Anti-Human CD35 Antibody[E11]
Product Specifications
Background
CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.
Abbreviation
CD35
Gene ID
1378
UniProt
P17927
Host
Mouse
Reactivity
Human
Target
C3BR; C3b/C4b receptor; CD35; CR1; Complement receptor type 1
Clonality
Monoclonal
Clone
E11
Conjugation
Biotin
Applications
FCM
Field of Research
Cell Biology; Complement; Immunology; Neuroinflammation; Neuroscience
Concentration
0.5 mg/mL
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Do not freeze.
Recommended Usage
6
Isotype
Mouse IgG1, κ
Available Sizes
Documents
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