Purified Anti-Human CD11a Antibody[TS1/22.1.1.13]
Product Specifications
Background
CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50) .
Abbreviation
CD11a
Gene ID
3683
UniProt
P20701
Host
Mouse
Reactivity
Human
Target
CD11 antigen-like family member A; CD11a; Integrin alpha-L; Itgal; LFA-1A; Ly-15; Lymphocyte antigen 15
Clonality
Monoclonal
Clone
TS1/22.1.1.13
Conjugation
Unconjugated
Applications
FCM
Field of Research
Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology; Innate Immunity; Neuroinflammation; Neuroscience
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Recommended Usage
6
Isotype
Mouse IgG1, κ
Available Sizes
Documents
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