PE Anti-Human CD45RA Antibody[HI100]
Product Specifications
Background
CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.
Abbreviation
CD45RA
Gene ID
5788
UniProt
P08575
Host
Mouse
Reactivity
Human
Target
CD45; L-CA; Ly-5; Ptprc; Receptor-type tyrosine-protein phosphatase C; T200
Clonality
Monoclonal
Clone
HI100
Conjugation
PE
Applications
FCM
Field of Research
Cell Biology; Immunology; Inhibitory Molecules; Neuroscience; Neuroscience Cell Markers
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG2b, κ
Available Sizes
Documents
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