Purified Anti-Mouse CD120b/TNFR2 Antibody[TR75-54.7]
Product Specifications
Background
CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β) . In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.
Abbreviation
CD120b/TNFR2
Gene ID
21938
UniProt
P25119
Host
Armenian Hamster
Reactivity
Mouse
Target
CD120b; TNF-R2; TNF-RII; TNFR-II; Tnfrsf1b; Tumor necrosis factor receptor 2; Tumor necrosis factor receptor superfamily member 1B; p75; p80 TNF-alpha receptor
Clonality
Monoclonal
Clone
TR75-54.7
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Innate Immunity
Concentration
≥ 1 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Recommended Usage
6
Isotype
Armenian Hamster IgG
Available Sizes
Documents
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
032277-APC 200 µL
ATP2C1, CT (ATP2C1, KIAA1347, PMR1L, Calcium-transporting ATPase type 2C member 1, ATP-dependent Ca (2+) pump PMR1) (APC) discontinued
Ask
View Details 