AF/LE Purified Anti-Mouse CD11a Antibody[FD441.8]

Product Specifications

Background

CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50) .

Abbreviation

CD11a

Gene ID

16408

UniProt

P24063

Host

Rat

Reactivity

Mouse

Target

CD11 antigen-like family member A; CD11a; Integrin alpha-L; Itgal; LFA-1A; Ly-15; Lymphocyte antigen 15

Clonality

Monoclonal

Clone

FD441.8

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology; Innate Immunity; Neuroinflammation; Neuroscience

Concentration

≥ 1 mg/mL

Dilution

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.