APC Anti-Mouse CD40 Antibody[FGK4.5/FGK45]
Product Specifications
Background
CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
Abbreviation
CD40
Gene ID
21939
UniProt
P27512
Host
Rat
Reactivity
Mouse
Target
B-cell surface antigen CD40; Bp50; CD40; CD40L receptor; Cd40; Tnfrsf5; Tumor necrosis factor receptor superfamily member 5
Clonality
Monoclonal
Clone
FGK4.5/FGK45
Conjugation
APC
Applications
FCM
Field of Research
Cell Biology; Costimulatory Molecules; Immunology; Neuroscience; Neuroscience Cell Markers
Concentration
0.2 mg/mL
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://www.mdpi.com/2218-273X/10/1/159
Citation 02
https://www.mdpi.com/2218-273x/10/1/159
Recommended Usage
6
Isotype
Rat IgG2a, κ
Available Sizes
Documents
Curated Selection
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