PE Anti-Mouse CD40 Antibody[FGK4.5/FGK45]

Product Specifications

Background

CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

Abbreviation

CD40

Gene ID

21939

UniProt

P27512

Host

Rat

Reactivity

Mouse

Target

B-cell surface antigen CD40; Bp50; CD40; CD40L receptor; Cd40; Tnfrsf5; Tumor necrosis factor receptor superfamily member 5

Clonality

Monoclonal

Clone

FGK4.5/FGK45

Conjugation

Applications

FCM

Field of Research

Cell Biology; Costimulatory Molecules; Immunology; Neuroscience; Neuroscience Cell Markers

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://www.sciencedirect.com/science/article/pii/S1385894723052051

Citation 02

https://www.sciencedirect.com/science/article/pii/S1567576923010962

Citation 03

https://www.sciencedirect.com/science/article/pii/S0378874125002223

Citation 04

https://www.sciencedirect.com/science/article/pii/S2772950822000899

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Rat IgG2a, κ

Available Sizes

Documents

Product Datasheet

Click to open

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

138215-01 100 g

Lithium Phosphate Extra Pure

Ask

View Details

138215-02 500 g

Lithium Phosphate Extra Pure

Ask

View Details

MBS6134790-01 0.1 mL

FHIT (Fragile Histidine Triad Gene, AP3A Hydrolase,bis(5'-adenosyl)-triphosphatase, Diadenosine 5',5'''-P1,P3-triphosphate Hydrolase, Dinucleosidetriphosphatase, Tumor Suppressor Protein, AP3Aase, FRA3B) (AP)

Ask

View Details

MBS6134790-02 5x 0.1 mL

FHIT (Fragile Histidine Triad Gene, AP3A Hydrolase,bis(5'-adenosyl)-triphosphatase, Diadenosine 5',5'''-P1,P3-triphosphate Hydrolase, Dinucleosidetriphosphatase, Tumor Suppressor Protein, AP3Aase, FRA3B) (AP)

Ask

View Details

MBS6250553-01 0.1 mL

CD4 (CD4 Antigen, CD4 Molecule, CD4 Receptor, CD4mut, T Cell Surface Antigen T4/Leu3, T Cell Antigen T4, T Cell Surface Glycoprotein CD4) (HRP)

Ask

View Details

MBS6250553-02 5x 0.1 mL

CD4 (CD4 Antigen, CD4 Molecule, CD4 Receptor, CD4mut, T Cell Surface Antigen T4/Leu3, T Cell Antigen T4, T Cell Surface Glycoprotein CD4) (HRP)

Ask

View Details