Purified Anti-Mouse CD127/IL-7RA Antibody[A7R34]
Product Specifications
Background
CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.
Abbreviation
CD127
UniProt
P16872
Host
Rat
Reactivity
Mouse
Target
CD127; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; Il7r; Interleukin-7 receptor subunit alpha
Clonality
Monoclonal
Clone
A7R34
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology
Concentration
≥ 1 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/ophvih
Product MSDS
https://789.bio/eb/TWf9GO
Recommended Usage
6
Isotype
Rat IgG2a, κ
Available Sizes
Curated Selection
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