Purified Anti-Mouse CD209b Antibody[22D1]
Product Specifications
Background
CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.
Abbreviation
CD209b
UniProt
Q8CJ91
Host
Armenian Hamster
Reactivity
Mouse
Target
CD209; CD209 antigen-like protein B; Cd209b; DC-SIGN-related protein 1; DC-SIGNR1; OtB7
Clonality
Monoclonal
Clone
22D1
Conjugation
Unconjugated
Applications
FCM
Concentration
≥ 1 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Recommended Usage
6
Isotype
Armenian Hamster IgG
Available Sizes
Documents
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