AF/LE Purified Anti-Mouse CD209b Antibody[22D1]
Product Specifications
Background
CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.
Abbreviation
CD209b
UniProt
Q8CJ91
Host
Armenian Hamster
Reactivity
Mouse
Target
CD209; CD209 antigen-like protein B; Cd209b; DC-SIGN-related protein 1; DC-SIGNR1; OtB7
Clonality
Monoclonal
Clone
22D1
Conjugation
None (AF/LE)
Applications
FCM
Concentration
≥ 1 mg/mL
Buffer
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Product Datasheet
https://789.bio/ea/ixhenl
Product MSDS
https://789.bio/eb/Xn58qL
Recommended Usage
6
Isotype
Armenian Hamster IgG
Available Sizes
Curated Selection
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