Purified Anti-Human/Mouse/Rat CD47 Antibody[MIAP410]
Product Specifications
Background
CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.
Abbreviation
CD47
Gene ID
16423;29364;961
UniProt
Q08722; Q61735; P97829
Host
Mouse
Reactivity
Human; Mouse; Rat
Target
Cd47; IAP; Integrin-associated protein; Leukocyte surface antigen CD47
Clonality
Monoclonal
Clone
MIAP410
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Innate Immunity
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Citation 01
https://pubs.acs.org/doi/abs/10.1021/acsami.3c11227
Recommended Usage
6
Isotype
Mouse IgG1, κ
Available Sizes
Documents
Curated Selection
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