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Biotin Anti-Mouse CD132 Antibody[3E12]

Product Specifications

Background

CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID) .

Abbreviation

CD132

Gene ID

16186

UniProt

P34902

Host

Rat

Reactivity

Mouse

Target

CD132; Cytokine receptor common subunit gamma; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG; Il2rg; Interleukin-2 receptor subunit gamma; gammaC; p64

Clonality

Monoclonal

Clone

3E12

Conjugation

Biotin

Applications

FCM

Field of Research

Immunology

Concentration

0.5 mg/mL

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Do not freeze.

Product Datasheet

https://789.bio/ea/b5uflo

Product MSDS

https://789.bio/eb/vH4mjP

Recommended Usage

6

Isotype

Rat IgG2b, κ

Available Sizes

Curated Selection

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