Purified Anti-Mouse CD132 Antibody[3E12]
Product Specifications
Background
CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID) .
Abbreviation
CD132
Gene ID
16186
UniProt
P34902
Host
Rat
Reactivity
Mouse
Target
CD132; Cytokine receptor common subunit gamma; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG; Il2rg; Interleukin-2 receptor subunit gamma; gammaC; p64
Clonality
Monoclonal
Clone
3E12
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology
Concentration
≥ 1 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Recommended Usage
6
Isotype
Rat IgG2b, κ
Available Sizes
Documents
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