APC Anti-Mouse CD3 Antibody[17A2]

Product Specifications

Background

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

Abbreviation

CD3

Gene ID

12500;12501;12502;12503

UniProt

P04235; P11942; P22646; P24161

Host

Rat

Reactivity

Mouse

Target

CD3; CD3E/D/G/Z; CD3e/d/g/z; T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain

Clonality

Monoclonal

Clone

17A2

Conjugation

APC

Applications

FCM

Field of Research

Immunology

Concentration

0.2 mg/mL

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.4c02183

Citation 02

https://www.sciencedirect.com/science/article/pii/S0264410X21016352

Citation 03

https://www.sciencedirect.com/science/article/pii/s0378874123000600

Citation 04

https://www.mdpi.com/1660-3397/20/3/197

Citation 05

https://www.nature.com/articles/s41598-022-19031-9

Citation 06

https://www.sciencedirect.com/science/article/pii/s0264410x21016352

Recommended Usage

Isotype

Rat IgG2b, κ

Available Sizes

Documents

Product Datasheet

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