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PE/Cyanine5 Anti-Mouse CD3 Antibody[17A2]

Product Specifications

Background

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

Abbreviation

CD3

Gene ID

12500;12501;12502;12503

UniProt

P04235; P11942; P22646; P24161

Host

Rat

Reactivity

Mouse

Target

CD3; CD3E/D/G/Z; CD3e/d/g/z; T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain

Clonality

Monoclonal

Clone

17A2

Conjugation

PE/Cyanine 5

Applications

FCM

Field of Research

Immunology

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://www.frontiersin.org/articles/10.3389/fphar.2024.1390170/full

Citation 02

https://www.mdpi.com/1999-4923/17/2/166

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Rat IgG2b, κ

Available Sizes

Curated Selection

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