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FITC Anti-Mouse CD3 Antibody[17A2]

Product Specifications

Background

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

Abbreviation

CD3

Gene ID

12500;12501;12502;12503

UniProt

P04235; P11942; P22646; P24161

Host

Rat

Reactivity

Mouse

Target

CD3; CD3E/D/G/Z; CD3e/d/g/z; T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain

Clonality

Monoclonal

Clone

17A2

Conjugation

FITC

Applications

FCM

Field of Research

Immunology

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://pmc.ncbi.nlm.nih.gov/articles/PMC11708301/

Citation 02

https://pubs.acs.org/doi/abs/10.1021/acsnano.3c04189

Citation 03

https://pubs.acs.org/doi/abs/10.1021/acsnano.3c10225

Citation 04

https://www.sciencedirect.com/science/article/pii/S1385894723070006

Citation 05

https://www.sciencedirect.com/science/article/pii/S138589472307002X

Citation 06

https://www.sciencedirect.com/science/article/pii/S1385894723044376

Citation 07

https://www.nature.com/articles/s41467-024-47111-z

Citation 08

https://www.sciencedirect.com/science/article/pii/S1385894724039548

Citation 09

https://onlinelibrary.wiley.com/doi/abs/10.1002/smll.202301019

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Rat IgG2b, κ

Available Sizes

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