PE/Cyanine5.5 Anti-Mouse CD62L Antibody[MEL-14]
Product Specifications
Background
CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naïve, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.
Abbreviation
CD62L
Gene ID
20343
UniProt
P18337
Host
Rat
Reactivity
Mouse
Target
CD62L; CD62 antigen-like family member L; L-selectin; LAM-1; LECAM1; Lnhr; Ly-22; Ly22; Lymph node homing receptor; Sell
Clonality
Monoclonal
Clone
MEL-14
Conjugation
PE/Cyanine 5.5
Applications
FCM
Field of Research
Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology; Innate Immunity
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Rat IgG2a, κ
Available Sizes
Documents
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