AF/LE Purified Anti-Human CD3 Antibody[OKT-3]
Product Specifications
Background
CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.
Abbreviation
CD3
Gene ID
916
UniProt
P07766
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD3 protein
Target
CD3E; CD3e; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E
Clonality
Monoclonal
Clone
OKT3
Conjugation
None (AF/LE)
Applications
FCM
Field of Research
Immunology
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Product Datasheet
https://cdn.gentaur.com/products/763/68dd14c4061270361e7d707c/datasheet/e-ab-f10010.pdf
Product MSDS
https://789.bio/eb/KKuTqH
Citation 01
https://isevjournals.onlinelibrary.wiley.com/doi/abs/10.1002/jev2.12490
Citation 02
https://www.liebertpub.com/doi/abs/10.1089/jir.2023.0043
Recommended Usage
6
Isotype
Mouse IgG2a, κ
Available Sizes
Curated Selection
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