AF/LE Purified Anti-Human CD3 Antibody[OKT-3]
Selected Variant
E-AB-F10010-01
Size: 100 µg
Product Specifications
Background
CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.
Abbreviation
CD3
Gene ID
916
UniProt
P07766
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD3 protein
Target
CD3E; CD3e; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E
Clonality
Monoclonal
Clone
OKT3
Conjugation
None (AF/LE)
Applications
FCM
Field of Research
Immunology
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Citation 01
https://isevjournals.onlinelibrary.wiley.com/doi/abs/10.1002/jev2.12490
Citation 02
https://www.liebertpub.com/doi/abs/10.1089/jir.2023.0043
Recommended Usage
6
Isotype
Mouse IgG2a, κ
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC470034-100 1x 100 µL
Cytokeratin 8/18 (C-51), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940304-500 1x 500 µL
CD106 / VCAM1 (B-K9), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740977-100 1x 100 µL
TGF-beta (1D11.16.8), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC401828-100 1x 100 µL
CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) (rKi-1/779), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details