FITC Anti-Mouse CD80 Antibody[16-10A1]

Product Specifications

Background

CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Abbreviation

CD80

Gene ID

12519

UniProt

Q00609

Host

Armenian Hamster

Reactivity

Mouse

Target

Activation B7-1 antigen; B7; Cd80; T-lymphocyte activation antigen CD80

Clonality

Monoclonal

Clone

16-10A1

Conjugation

FITC

Applications

FCM

Field of Research

Cell Biology; Costimulatory Molecules; Immunology; Neuroscience; Neuroscience Cell Markers

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://www.nature.com/articles/s41467-023-40826-5

Citation 02

https://pubs.acs.org/doi/abs/10.1021/acsnano.4c07213

Citation 03

https://pubs.acs.org/doi/abs/10.1021/acsnano.4c16788

Citation 04

https://www.sciencedirect.com/science/article/pii/S1385894724035204

Citation 05

https://www.sciencedirect.com/science/article/pii/S0142961225000158

Citation 06

https://www.sciencedirect.com/science/article/pii/S0142961224000085

Citation 07

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157729/

Citation 08

https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-023-01803-8

Citation 09

https://onlinelibrary.wiley.com/doi/abs/10.1002/adhm.202300028

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Armenian Hamster IgG

Available Sizes

Documents

Product Datasheet

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