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PE/Cyanine7 Anti-Mouse CD11c Antibody[N418]

Product Specifications

Background

CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18) . It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.

Abbreviation

CD11c

Gene ID

16411

UniProt

Q9QXH4

Host

Armenian Hamster

Reactivity

Mouse

Target

CD11 antigen-like family member C; CD11c; Integrin alpha-X; Itgax; Leukocyte adhesion receptor p150+95

Clonality

Monoclonal

Clone

N418

Conjugation

PE/Cyanine 7

Applications

FCM

Field of Research

Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology; Innate Immunity; Neuroscience; Neuroscience Cell Markers

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://link.springer.com/article/10.1186/s13046-025-03324-8

Citation 02

https://www.sciencedirect.com/science/article/pii/S0264127525000516

Citation 03

https://www.sciencedirect.com/science/article/pii/S0141813024038728

Citation 04

https://www.mdpi.com/1422-0067/25/14/7765

Citation 05

https://link.springer.com/article/10.1007/s00262-025-03949-w

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Armenian Hamster IgG

Available Sizes

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