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APC Anti-Mouse CD11c Antibody[N418]

Product Specifications

Background

CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18) . It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.

Abbreviation

CD11c

Gene ID

16411

UniProt

Q9QXH4

Host

Armenian Hamster

Reactivity

Mouse

Target

CD11 antigen-like family member C; CD11c; Integrin alpha-X; Itgax; Leukocyte adhesion receptor p150+95

Clonality

Monoclonal

Clone

N418

Conjugation

APC

Applications

FCM

Field of Research

Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology; Innate Immunity; Neuroscience; Neuroscience Cell Markers

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://pubs.acs.org/doi/abs/10.1021/acsnano.4c18954

Citation 02

https://advanced.onlinelibrary.wiley.com/doi/abs/10.1002/advs.202415227

Citation 03

https://www.sciencedirect.com/science/article/pii/S0142961225003102

Citation 04

https://www.sciencedirect.com/science/article/pii/S0142961225000158

Citation 05

https://www.sciencedirect.com/science/article/pii/S0142961224000085

Citation 06

https://onlinelibrary.wiley.com/doi/abs/10.1002/adhm.202301401

Citation 07

https://link.springer.com/article/10.1186/s12951-025-03405-y

Citation 08

https://www.sciencedirect.com/science/article/pii/S1742706124004653

Citation 09

https://pubmed.ncbi.nlm.nih.gov/37804510/

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Armenian Hamster IgG

Available Sizes

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