APC Anti-Mouse CD161/NK1.1 Antibody[PK136]
Product Specifications
Background
NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.
Abbreviation
CD161
Gene ID
17059;80782
UniProt
P27814; P27812; Q99JB4
Host
Mouse
Reactivity
Mouse
Target
CD161 antigen-like family member C; CD161; NK1.1; CD161c; Killer cell lectin-like receptor subfamily B member 1C; Klrb1c; Ly-55c; NKR-P1 40; NKR-P1.9; NKR-P1C
Clonality
Monoclonal
Clone
PK136
Conjugation
APC
Applications
FCM
Field of Research
Immunology; Innate Immunity
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation 01
https://link.springer.com/article/10.1007/s00210-023-02855-1
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG2a, κ
Available Sizes
Documents
Curated Selection
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