PE Anti-Mouse CD161/NK1.1 Antibody[PK136]

Product Specifications

Background

NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

Abbreviation

CD161

Gene ID

17059;80782

UniProt

P27814; P27812; Q99JB4

Host

Mouse

Reactivity

Mouse

Target

CD161 antigen-like family member C; CD161; NK1.1; CD161c; Killer cell lectin-like receptor subfamily B member 1C; Klrb1c; Ly-55c; NKR-P1 40; NKR-P1.9; NKR-P1C

Clonality

Monoclonal

Clone

PK136

Conjugation

Applications

FCM

Field of Research

Immunology; Innate Immunity

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://aacrjournals.org/cancerres/article/doi/10.1158/0008-5472.CAN-24-1817/749964

Citation 02

https://www.sciencedirect.com/science/article/pii/S0891584925000528

Citation 03

https://www.sciencedirect.com/science/article/pii/S0024320525003480

Citation 04

https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1584411/full

Citation 05

https://pmc.ncbi.nlm.nih.gov/articles/PMC11866255/

Recommended Usage

The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

Isotype

Mouse IgG2a, κ

Available Sizes

Documents

Product Datasheet

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