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Angiotensin I Converting Enzyme 2 (ACE2) Inhibitor Screening Kit

Product Specifications

Type

Fluorometric method

Field of Research

Inhibitor Screening

Assay Principle

Angiotensin converting enzyme 2 (ACE2) is an important component of the renin angiotensin system (RAS) . ACE2 is a negative regulatory factor of RAS, which can balance multiple functions of ACE. By regulating angiotensin II, ACE2 can cleave angiotensin II into Ang1-7, which has active effects such as protecting the heart and relaxing blood vessels. It is also one of the key active receptors in the field of pharmaceutical science research. The principle of this kit is that ACE2 catalyzes the decomposition of substrates, releasing fluorescent products. Adding inhibitors can inhibit the fluorescence value, and the inhibition ability of inhibitors can be determined by the fluorescence value

Assay Performance Time

45 min

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at -20°C for 12 months with shading light.

Inter CV

10.5%

Intra CV

0.8%

Detection Instrument

Fluorescence Microplate reader

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