MEK4 inhibitor-1
MEK4 inhibitor-1 is a novel MEK4 inhibitor against pancreatic adenocarcinoma with an IC50 value of 61 nM.
Product Specifications
CAS Number
2570386-36-4
UNSPSC
12352005
Target
MEK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mek4-inhibitor-1.html
Purity
98.89
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(C(C2=CC=C(S(=O)(N)=O)C=C2)=NN3)C3=C1
Molecular Formula
C13H10FN3O2S
Molecular Weight
291.30
References & Citations
[1]Kwong AJ, et al. Rational Design, Optimization, and Biological Evaluation of Novel MEK4 Inhibitors against Pancreatic Adenocarcinoma. ACS Med Chem Lett. 2021 Sep 15;12 (10) :1559-1567.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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