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Suc-AAPR-pNA

Product Specifications

UNSPSC Description

Suc-AAPR-pNA is a substrate of trypsin acyl-enzymes. Suc-AAPR-pNA can be used to test trypsin acyl-enzymes activity[1][2].

Target Antigen

Ser/Thr Protease

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/suc-aapr-pna.html

Solubility

10 mM in DMSO

Smiles

O=[N+]([O-])C(C=C1)=CC=C1NC([C@H](CCCNC(N)=N)NC([C@H]2N(CCC2)C([C@H](C)NC([C@H](C)NC(CCC(O)=O)=O)=O)=O)=O)=O

Molecular Weight

633.65

References & Citations

[1]DeSantis G, et, al. Toward tailoring the specificity of the S1 pocket of subtilisin B. lentus: chemical modification of mutant enzymes as a strategy for removing specificity limitations. Biochemistry. 1999 Oct 5;38(40):13391-7.|[2]Radisky ES, et, al. Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates. Proc Natl Acad Sci U S A. 2006 May 2;103(18):6835-40.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P4477/Suc-AAPR-pNA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P4477/

Clinical Information

No Development Reported

CAS Number

131068-47-8

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