Suc-AAPR-pNA

Suc-AAPR-pNA is a substrate of trypsin acyl-enzymes. Suc-AAPR-pNA can be used to test trypsin acyl-enzymes activity[1][2].

Product Specifications

CAS Number

[131068-47-8]

UNSPSC

12352209

Target

Ser/Thr Protease

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/suc-aapr-pna.html

Solubility

10 mM in DMSO

Smiles

O=[N+]([O-])C(C=C1)=CC=C1NC([C@H](CCCNC(N)=N)NC([C@H]2N(CCC2)C([C@H](C)NC([C@H](C)NC(CCC(O)=O)=O)=O)=O)=O)=O

Molecular Formula

C27H39N9O9

Molecular Weight

633.65

References & Citations

[1]DeSantis G, et, al. Toward tailoring the specificity of the S1 pocket of subtilisin B. lentus: chemical modification of mutant enzymes as a strategy for removing specificity limitations. Biochemistry. 1999 Oct 5;38 (40) :13391-7.|[2]Radisky ES, et, al. Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates. Proc Natl Acad Sci U S A. 2006 May 2;103 (18) :6835-40.