FK 453
FK 453 (compound 1d) is a potent and selective adenosine A1 receptor antagonist with an IC50 value of 17.2 nM[1].
Product Specifications
CAS Number
[121524-18-3]
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fk-453.html
Purity
99.20
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(/C=C/C1=C2C=CC=CN2N=C1C3=CC=CC=C3)N4[C@@H](CCO)CCCC4
Molecular Formula
C23H25N3O2
Molecular Weight
375.46
References & Citations
[1]Atsushi Akahane, et al. Discovery of FK453, a novel non-xanthine adenosine A1 receptor antagonist. Bioorganic & Medicinal Chemistry Letters. 1996, 16, 7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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