Flavanone (Standard)
Flavanone (Standard) is the analytical standard of Flavanone. This product is intended for research and analytical applications. Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase) . lavanone is the inhibitor for ERK/p38/NF-κB signaling pathway. Flavanone exhibits oral activity and antitumor efficacy[1][2].
Product Specifications
CAS Number
487-26-3
UNSPSC
12352005
Target
Cytochrome P450; ERK; MMP; NF-κB; p38 MAPK; PAI-1; Reference Standards
Type
Reference Standards
Related Pathways
MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Others; Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/flavanone-standard.html
Smiles
O=C1CC(C2=CC=CC=C2)OC3=CC=CC=C13
Molecular Formula
C15H12O2
Molecular Weight
224.25
References & Citations
[1]JT Kellis Jr, et al. Inhibition of human estrogen synthetase (aromatase) by flavones. Science. 1984 Sep. 225 (4666) :1032-1034.|[2]Hsiao YC, et al., Flavanone and 2'-OH flavanone inhibit metastasis of lung cancer cells via down-regulation of proteinases activities and MAPK pathway. Chem Biol Interact. 2007 May 1;167 (3) :193-206.|[3]Hsiao YC, et al., The tumor-growth inhibitory activity of flavanone and 2'-OH flavanone in vitro and in vivo through induction of cell cycle arrest and suppression of cyclins and CDKs. J Biomed Sci. 2007 Jan;14 (1) :107-19.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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