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Recombinant Human Growth-regulated alpha protein (CXCL1) (Active)

Product Specifications

Background

Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha (4-73), GRO-alpha (5-73) and GRO-alpha (6-73) show a 30-fold higher chemotactic activity. {ECO:0000269|PubMed:10095777}.

Product Name Alternative

C-X-C motif chemokine 1 Melanoma growth stimulatory activity, MGSA, Neutrophil-activating protein 3

Gene ID

2919

UniProt

P09341

Target

ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKNGRKA CLNPASPIVK KIIEKMLNSD KSN

Purification

>97% as determined by SDS-PAGE and HPLC.

Bioactivity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration range of 10-50 ng, ml.

Storage Conditions

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Calculated Molecular Weight

7.9 kDa

Formulation

0.2 ?m filtered PBS, pH 7.4 , lyophilized

Host or Source

E.Coli

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