EGLU
EGLU ((2S) -α-Ethylglutamic acid; (2S) -α-EGLU) is a potent and competitive mGluR-2 receptor antagonist. EGLU interacts with (lS,3S) -ACPD-sensitive site with a Kd value of 66 μM. EGLU is an antidepressant agent[1].
Product Specifications
CAS Number
170984-72-2
Product Name Alternative
(2S) -α-Ethylglutamic acid; (2S) -α-EGLU
UNSPSC
12352211
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/eglu.html
Purity
99.79
Solubility
H2O : 125 mg/mL (ultrasonic)
Smiles
N[C@](CCC(O)=O)(CC)C(O)=O
Molecular Formula
C7H13NO4
Molecular Weight
175.18
References & Citations
[1]Jane DE, et al. Potent antagonists at the L-AP4- and (1S,3S) -ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord.Neuropharmacology. 1996;35 (8) :1029-35.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR2
Available Sizes
Frequently Asked Questions
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