EGLU

EGLU ((2S) -α-Ethylglutamic acid; (2S) -α-EGLU) is a potent and competitive mGluR-2 receptor antagonist. EGLU interacts with (lS,3S) -ACPD-sensitive site with a Kd value of 66 μM. EGLU is an antidepressant agent[1].

Product Specifications

CAS Number

[170984-72-2]

Product Name Alternative

(2S) -α-Ethylglutamic acid; (2S) -α-EGLU

UNSPSC

12352211

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/eglu.html

Purity

99.79

Solubility

H2O : 125 mg/mL (ultrasonic)

Smiles

N[C@](CCC(O)=O)(CC)C(O)=O

Molecular Formula

C7H13NO4

Molecular Weight

175.18

References & Citations

[1]Jane DE, et al. Potent antagonists at the L-AP4- and (1S,3S) -ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord.Neuropharmacology. 1996;35 (8) :1029-35.