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Syk-IN-11

Syk-IN-11 (BIIB-057) is a selective Syk inhibitor with an IC50 Of 13 nM. Syk-IN-11 can be used in the study of arthritis and chronic lymphocytic leukemia[1].

Product Specifications

CAS Number

1194954-83-0

UNSPSC

12352005

Target

Syk

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/syk-in-11.html

Smiles

O=C(C1=CN=C(N[C@H]2[C@@H](N)CCCC2)N=C1NC3=CC=C(N4N=CC=N4)C=C3)N

Molecular Formula

C19H23N9O

Molecular Weight

393.45

References & Citations

[1]Lucas MC, et al. Small-molecule inhibitors of spleen tyrosine kinase as therapeutic agents for immune disorders: will promise meet expectations? Future Med Chem. 2014;6 (16) :1811-27.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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