Pomalidomide 5-piperidylamine

Pomalidomide 5-piperidylamine is the conjugate of an E3 ligase ligand and a linker. Pomalidomide 5-piperidylamine can be used for synthesis of PROTAC PARP1 degrader-2 (HY-164306) [1].

Product Specifications

CAS Number

[2636798-55-3]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pomalidomide-5-piperidylamine.html

Smiles

O=C1C2=CC=C(N3CCC(CC3)N)C=C2C(N1C4C(NC(CC4)=O)=O)=O

Molecular Formula

C18H20N4O4

Molecular Weight

356.38

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Li Y, et al., Parp-1 degradation agent and use thereof. WO2023066363.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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