(R, R) -S63845
(R, R) -S63845 is the isomer of S63845 , and can be used as an experimental control. S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor with a Kd of 0.19 nM for human MCL1[1].
Product Specifications
UNSPSC
12352005
Target
Bcl-2 Family; Drug Isomer
Type
Reference compound
Related Pathways
Apoptosis; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-r-s63845.html
Purity
99.32
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC([C@H](OC1=C2[C@@]([C@@]3=C(C)C(Cl)=C(OCCN4CCN(CC4)C)C=C3)=C(SC2=NC=N1)C5=CC=C(O5)F)CC6=C(OCC7=CC=NN7CC(F)(F)F)C=CC=C6)=O
Molecular Formula
C39H37ClF4N6O6S
Molecular Weight
829.26
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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