6'-Sialyllactose (sodium)

6'-Sialyllactose sodium promotes the growth of beneficial bacteria (such as Bifidobacterium and lactobacillus) and inhibits the proliferation of harmful bacteria. 6'-Sialyllactose sodium exhibits anti-inflammatory and anti-angiogenic activities. 6'-Sialyllactose sodium promotes the muscle health[1][2][3][4].

Product Specifications

CAS Number

[157574-76-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Akt; Bacterial; ERK; VEGFR

Type

Reference compound

Related Pathways

Anti-infection; MAPK/ERK Pathway; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/6-sialyllactose-sodium.html

Purity

98.0

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C([C@](O[C@@]([C@@H]1NC(C)=O)([H])[C@H](O)[C@H](O)CO)(C[C@@H]1O)OC[C@H]([C@@H]([C@@H]2O)O)O[C@H]([C@@H]2O)O[C@H]([C@H](O)CO)[C@H](O)[C@@H](O)C=O)O[Na]

Molecular Formula

C23H38NNaO19

Molecular Weight

655.53

Precautions

H302, H315, H319, H335

References & Citations

[1]MariarosariaMarotta, et al. The predominant milk oligosaccharide 6′-sialyllactose reduces the internalisation of Pseudomonas aeruginosa in human pneumocytes. Journal of Functional Foods Volume 6, January 2014, Pages 367-373.|[2]Tarr AJ, et al., The prebiotics 3'Sialyllactose and 6'Sialyllactose diminish stressor-induced anxiety-like behavior and colonic microbiota alterations: Evidence for effects on the gut-brain axis. Brain Behav Immun. 2015 Nov;50:166-177.|[3]Park EJ, et al., 6'-Sialyllactose Enhances Exercise Performance via Increased Muscle Mass and Strength. Nutrients. 2024 Aug 7;16 (16) :2600.|[4]Kim EY, et al., 6-sialyllactose ameliorates dihydrotestosterone-induced benign prostatic hyperplasia through suppressing VEGF-mediated angiogenesis. BMB Rep. 2019 Sep;52 (9) :560-565.