Tilogotamab
Tilogotamab is an agonistic hexamer formation-enhanced mixture of two antibodies that target two separate epitopes on death receptor type 5 (DR5) . Tilogotamab specifically binds to and activates DR5. Tilogotamab can be used for the research of multiple myeloma (MM) [1].
Product Specifications
CAS Number
2109731-10-2
Product Name Alternative
HexaBody-DR5/DR5; Hx-DR5-01/05
UNSPSC
12352203
Target
Others
Type
Inhibitory Antibodies
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tilogotamab.html
Purity
99.31
Solubility
H2O
Smiles
[Tilogotamab]
Molecular Weight
(144.88 kDa)
References & Citations
[1]Horst HJ, et, al. Potent preclinical activity of HexaBody-DR5/DR5 in relapsed and/or refractory multiple myeloma. Blood Adv. 2021 Apr 27;5 (8) :2165-2172.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2
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