Dopamine D2 receptor agonist-3

Dopamine D2 receptor agonist-3 (compound 3) is a selective D2 receptor partial agonist and Dopamine D3 receptor antagonist (with pEC50 of 8.3 and [1].

Product Specifications

CAS Number

[1257326-24-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dopamine-d2-receptor-agonist-3.html

Purity

98.30

Solubility

DMSO : 3 mg/mL (ultrasonic)

Smiles

O=C1N(CC2NCCCC2)CCN1C3=CC=CC=C3.[H]Cl

Molecular Formula

C15H22ClN3O

Molecular Weight

295.81

Precautions

H302, H315, H319, H335

References & Citations

[1]Holmes IP, et al. The identification of a selective dopamine D2 partial agonist, D3 antagonist displaying high levels of brain exposure. Bioorg Med Chem Lett. 2010 Mar 15;20 (6) :2013-6.