Zemprocitinib
Product Specifications
CAS Number
2417414-44-7
UNSPSC Description
Zemprocitinib (Compound 1) is a Janus kinase (JAK) inhibitor. The IC50 values for JAK1, JAK2 and TYK2 are 5.95, 141.3 and 119 nM, respectively[1].
Target Antigen
JAK
Type
Reference compound
Related Pathways
Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zemprocitinib.html
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=S(NC12CC(C1)(C2)N3C=NC4=CNC5=NC=CC5=C43)(CCC)=O
Molecular Weight
345.42
References & Citations
[1]Zhaokui WAN, et al. Tricyclic janus kinase 1 inhibitors, and compositions and methods thereof. WO2020088659A1. 2020-05-07.
Shipping Conditions
Blue Ice
Clinical Information
No Development Reported
Available Sizes
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