ALDH1A1-IN-2
ALDH1A1-IN-2 is a potent inhibitor of aldehyde dehydrogenase 1a1 (aldh1a1) . Aldehyde dehydrogenases (ALDH) constitute a family of enzymes that play a critical role in oxidizing various cytotoxic xenogenic and biogenic aldehydes. ALDH1A1-IN-2 has the potential for the research of cancer, inflammation, or obesity (extracted from patent WO2019089626A1, compound 295) [1].
Product Specifications
CAS Number
[2231081-18-6]
UNSPSC
12352005
Target
Aldehyde Dehydrogenase (ALDH)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aldh1a1-in-2.html
Purity
99.31
Solubility
DMSO : 1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
N#CC1(C2=CC=C(C3=C(C(N4CCN(S(=O)(C)=O)CC4)=O)C=NC5=CC=C(Cl)C=C35)C=C2)CC1
Molecular Formula
C25H23ClN4O3S
Molecular Weight
494.99
References & Citations
[1]Shyh Ming YANG, et al. Substituted quinoline analogs as aldehyde dehydrogenase 1a1 (aldh1a1) inhibitors. Patent WO2019089626A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ALDH1
Available Sizes
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