Nudifloramide-d3
Nudifloramide-d3 (2PY-d3) is the deuterium labeled Nudifloramide. Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly (ADP-ribose) polymerase (PARP-1) activity in vitro[1].
Product Specifications
CAS Number
1207384-48-2
UNSPSC
12352005
Target
Endogenous Metabolite; PARP
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Purity
99.47
Solubility
10 mM in DMSO|H2O : 33.33mg/mL (ultrasonic)
Smiles
C(N)(=O)C1=CN(C([2H])([2H])[2H])C(=O)C=C1
Molecular Formula
C7H5D3N2O2
Molecular Weight
155.17
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Rutkowski B, et al. N-methyl-2-pyridone-5-carboxamide: a novel uremic toxin? Kidney Int Suppl. 2003 May; (84) :S19-21.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TA813576AM 100 µL
CD133 (PROM1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5D5]
Sign In for Pricing
View Details