NPY5RA-972
NPY5RA-972 is an orally active, central nervous system (CNS) penetrating, potent and selective NPY Y5 receptor antagonist that prevents feeding driven by activation of this receptor[1].
Product Specifications
CAS Number
[439861-56-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Neuropeptide Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/npy5ra-972.html
Purity
98.99
Solubility
DMSO : 16.67 mg/mL (ultrasonic)
Smiles
O=C(N1CCOCC1)NC2=C(C)C(C3=CC=CC=C3N4C(C)C)=C4C=C2
Molecular Formula
C21H25N3O2
Molecular Weight
351.45
Precautions
H302, H315, H319, H335
References & Citations
[1]Andrew V Turnbull, et al. Selective antagonism of the NPY Y5 receptor does not have a major effect on feeding in rats. Diabetes. 2002 Aug;51 (8) :2441-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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