Ro60-0175 (fumarate)
Ro60-0175 fumarate is a potent and selective agonist of 5-HT2C receptor[1].
Product Specifications
CAS Number
169675-09-6
UNSPSC
12352005
Hazard Statement
H315-H319
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ro60-0175-fumarate.html
Concentration
10mM
Purity
99.47
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N[C@@H](C)CN1C=CC2=C1C=C(Cl)C(F)=C2.OC(/C=C/C(O)=O)=O
Molecular Formula
C15H16ClFN2O4
Molecular Weight
342.75
Precautions
P264-P280-P302+P352-P305+P351+P338-P362+P364
References & Citations
[1]Fletcher PJ, et al. The 5-HT2C receptor agonist Ro60-0175 reduces cocaine self-administration and reinstatement induced by the stressor yohimbine, and contextual cues. Neuropsychopharmacology. 2008;33 (6) :1402-1412.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor; α-1 microglobulin
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